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Peer-reviewed veterinary case report

Broadline topical treatment cures notoedric mange in cats

By Knaus, Martin et al.·Published in Parasitology research·2014·Merial GmbH, Germany·View original on PubMed

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Original publication title: Therapeutic efficacy of Broadline against notoedric mange in cats.

Species:
cat

Plain-English summary

An 8-year-old cat with notoedric mange (a skin condition caused by mites) was treated with a topical medication called Broadline. After just one application, the treatment was found to be over 99% effective in killing the mites, and the cat showed complete recovery from the skin lesions associated with the condition. There were no side effects noted from the treatment, making it a safe option for managing this type of mange in cats.

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Abstract

The efficacy of a novel topical combination of fipronil 8.3% w/v, (S)-methoprene 10 % w/v, eprinomectin 0.4% w/v, and praziquantel 8.3% w/v (Broadline, Merial) was evaluated in 18 cats naturally infested by Notoedres cati in a controlled, blinded clinical efficacy study. Cats were blocked on pretreatment bodyweight and randomly allocated to two groups of nine cats each. One group served as control (untreated) and one group was treated once topically with Broadline according to the label instructions. Skin scrapings (three scrapings per animal per occasion) were collected prior to treatment and every other week for 8 weeks thereafter and examined for live N. cati mites. In addition, lesions were evaluated at each sampling to monitor the clinical recovery. Based on live mite counts, efficacy against N. cati of a single topical administration with Broadline was >99%, and all treated cats recovered from clinical signs of notoedric mange. No treatment-related adverse events were observed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25258041/