Peer-reviewed veterinary case report
Three cases of idiopathic sterile pyogranulomatous inflammation of epidural fat in Miniature Dachshunds.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2012
- Authors:
- Nishida, Hidetaka et al.
- Affiliation:
- Nakayama Veterinary Hospital · Japan
- Species:
- dog
Plain-English summary
Three Miniature Dachshunds were experiencing worsening coordination and paralysis due to a condition called idiopathic sterile pyogranulomatous inflammation of the fat around their spinal cord. To treat this, the dogs underwent surgery to remove the material pressing on their spinal cords. After the surgery, one dog did not regain movement or feeling, while two others showed some improvement but later had a return of their symptoms. For the two dogs that improved, a medication called cyclosporine helped them stay better for a longer time. Overall, the treatment worked for some, but not all, of the dogs involved.
Abstract
Progressive ataxia and paralysis in three Miniature Dachshunds were found to be caused by idiopathic sterile pyogranulomatous inflammation of epidural fat between T5 and L4. All dogs were managed by hemilaminectomy and removal of epidural compressive material. Surgical findings and histopathological evaluation were necessary to diagnose epidural pyogranulomatous inflammation. A dog did not regain motor and sensor function after the surgery. Two dogs had exhibited improved neurological function after the surgery, but they recurred. Oral cyclosporine treatment was useful for their long remission. Idiopathic sterile pyogranulomatous inflammation of epidural fat can be considered to be a cause of thoracolumbar myelopathy in dogs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22467074/