Peer-reviewed veterinary case report
Radiation therapy with or without surgery for brain tumors in dogs
By Keyerleber, M A et al.·Published in Veterinary and comparative oncology·2015·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Three-dimensional conformal radiation therapy alone or in combination with surgery for treatment of canine intracranial meningiomas.
- Species:
- dog
Plain-English summary
A group of 31 dogs with brain tumors called meningiomas underwent treatment with a type of radiation therapy known as three-dimensional conformal radiation therapy (3D-CRT). Some dogs received this treatment alone, while others had it after surgery. The dogs treated with 3D-CRT had a median survival time of about 577 days, and those who died specifically from the tumor lived around 906 days on average. The study suggests that 3D-CRT could be a good option for treating these tumors, possibly even without surgery.
People also search for: dog brain tumor treatment · meningioma in dogs · radiation therapy for dogs · dog survival rates meningioma · canine brain cancer options
Abstract
Treatment protocols, treatment planning methods and tumour types in studies evaluating radiotherapy for canine brain tumours have been varied. This case series retrospectively evaluated the outcome of definitive, three-dimensional conformal radiation therapy (3D-CRT) as either a sole modality or as an adjuvant to surgery in 31 dogs diagnosed with meningioma by histopathology (n = 10) or cross-sectional imaging of the head (n = 21, assessed independently by two board certified radiologists). Prescribed dose ranged from 45 to 54 Gy in 2.5 to 3 Gy fractions. Median overall survival was 577 days (interquartile range = 272-829 days; range = 30-1942 days) when all deaths were considered and 906 days (interquartile range = 336-912 days; range = 10 -1942 days) when only dogs dying due to meningioma were considered. No significant difference in survival time was detected for the defined clinical or imaging findings or between treatment with radiotherapy alone versus adjuvant radiotherapy, suggesting that 3D-CRT may be a viable alternative to surgery.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23869984/