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Peer-reviewed veterinary case report

Three-dimensional impedance map analysis of rabbit liver.

Journal:
The Journal of the Acoustical Society of America
Year:
2011
Authors:
Pawlicki, Alexander D et al.
Affiliation:
Department of Electrical and Computer Engineering · United States
Species:
rabbit

Abstract

Three-dimensional impedance maps (3DZMs) are computational models of acoustic impedance of tissue constructed from histology images. 3DZMs can be analyzed to estimate model-based quantitative ultrasound parameters such as effective scatterer diameter (ESD). In this study, 3DZMs were constructed from normal and fatty rabbit livers. Estimates of ESD were made using the fluid-filled sphere scattering model. Weighting toward smaller scatterer sizes produced ESD estimates of 7.5  ±  1.3 and 7.0  ±  0.3 μm for normal and fatty liver, respectively, approximately the size of a liver cell nucleus. This suggests the nucleus could be a primary source of scattering in liver.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22088037/