Peer-reviewed veterinary case report
Cats protected for 3 years after vaccination against 3 viruses
By Gore, Thomas C et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2006·Intervet Inc., United States·View original on PubMed →
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Original publication title: Three-year duration of immunity in cats following vaccination against feline rhinotracheitis virus, feline calicivirus, and feline panleukopenia virus.
- Species:
- cat
Plain-English summary
A group of 42 cats received vaccinations against three serious viruses: feline rhinotracheitis virus, feline calicivirus, and feline panleukopenia virus, starting at 8 weeks old. After being kept isolated for three years, these vaccinated cats were exposed to the viruses, and they showed significantly fewer symptoms compared to unvaccinated cats. In fact, all vaccinated cats were completely protected from severe oral ulcers and disease caused by these viruses. This study confirms that the vaccine offers strong protection for at least three years after the second shot.
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Abstract
Forty-two seronegative cats received an initial vaccination at 8 weeks of age and a booster vaccination at 12 weeks. All cats were kept in strict isolation for 3 years after the second vaccination and then were challenged with feline calicivirus (FCV) or sequentially challenged with feline rhinotracheitis virus (FRV) followed by feline panleukopenia virus (FPV). For each viral challenge, a separate group of 10 age-matched, nonvaccinated control cats was also challenged. Vaccinated cats showed a statistically significant reduction in virulent FRV-associated clinical signs (P = .015), 100% protection against oral ulcerations associated with FCV infection (P < .001), and 100% protection against disease associated with virulent FPV challenge (P < .005). These results demonstrated that the vaccine provided protection against virulent FRV, FCV, and FPV challenge in cats 8 weeks of age or older for a minimum of 3 years following second vaccination.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17039444/