Peer-reviewed veterinary case report
Dogs protected for 3 years after vaccine against adenovirus
By Gore, Thomas C et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2005·Intervet Inc, United States·View original on PubMed →
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Original publication title: Three-year duration of immunity in dogs following vaccination against canine adenovirus type-1, canine parvovirus, and canine distemper virus.
- Species:
- dog
Plain-English summary
A group of puppies received a new vaccine to protect against serious diseases like canine adenovirus, parvovirus, and distemper at 7 and 11 weeks old. After being kept isolated for three years, these vaccinated dogs were exposed to the viruses, and none showed any signs of illness. This study shows that the vaccine provides strong protection for at least three years after the second dose. If you're considering vaccinations for your puppy, this new vaccine could be a great option for long-lasting immunity.
People also search for: puppy vaccination schedule · canine parvovirus vaccine effectiveness · how long does dog vaccine immunity last
Abstract
A challenge-of-immunity study was conducted to demonstrate immunity in dogs 3 years after their second vaccination with a new multivalent, modified-live vaccine containing canine adenovirus type 2 (CAV-2), canine parvovirus (CPV), and canine distemper virus (CDV). Twenty-three seronegative pups were vaccinated at 7 and 11 weeks of age. Eighteen seronegative pups, randomized into groups of six dogs, served as challenge controls. Dogs were kept in strict isolation for 3 years following the vaccination and then challenged sequentially with virulent canine adenovirus type 1 (CAV-1), CPV, and CDV. For each viral challenge, a separate group of six control dogs was also challenged. Clinical signs of CAV-1, CPV, and CDV infections were prevented in 100% of vaccinated dogs, demonstrating that the multivalent, modified-live test vaccine provided protection against virulent CAV-1, CPV, and CDV challenge in dogs 7 weeks of age or older for a minimum of 3 years following second vaccination.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15906266/