Peer-reviewed veterinary case report
Dog with traumatic bleeding improved after epsilon-aminocaproic acid
By Yoo, Seung H et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2016·Department of Microbiology·View original on PubMed →
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Original publication title: Thromboelastographic evidence of inhibition of fibrinolysis after ε-aminocaproic acid administration in a dog with suspected acute traumatic coagulopathy.
- Species:
- dog
Plain-English summary
A 9-year-old female Airedale Terrier was brought to the vet after being injured in a car accident, suffering from multiple wounds and a diaphragmatic hernia. Despite several blood transfusions and surgeries, she continued to bleed heavily from her chest. The vet started her on a medication called ε-aminocaproic acid, which helped stop the bleeding and improved her condition quickly. This treatment showed that it effectively reduced the dog's excessive bleeding after trauma.
People also search for: dog bleeding after car accident · Airedale Terrier trauma treatment · ε-aminocaproic acid for dogs
Abstract
OBJECTIVE: To describe the thromboelastographic changes in fibrinolysis with ε-aminocaproic acid treatment in a dog with suspected acute traumatic coagulopathy. CASE SUMMARY: A 9-year-old female spayed Airedale Terrier was presented with multiple injuries consistent with motor vehicle trauma. After surgical repair of a diaphragmatic hernia and minor laceration of the right cranial lung lobe, the dog continued to produce copious volumes of hemorrhagic fluid from the thoracic cavity despite multiple plasma transfusions, autotransfusions, and failure to locate a definitive source of bleeding during 2 separate surgeries. ε-Aminocaproic acid treatment was initiated and was associated with rapid clinical improvement and diminished fibrinolysis based on a modified plasma-based thromboelastogram. NEW OR UNIQUE INFORMATION PROVIDED: This report describes thromboelastographic evidence of inhibition of fibrinolysis after ε-aminocaproic acid administration in a dog with suspected acute traumatic coagulopathy. Thromboelastrography may be useful in monitoring therapy with antifibrinolytic drugs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26990227/