Peer-reviewed veterinary case report
Thrombotic thrombocytopenic purpura related to ADAMTS13 deficiency, and successful treatment in a chimpanzee (Pan troglodytes verus).
- Journal:
- Journal of medical primatology
- Year:
- 2017
- Authors:
- van Bolhuis, Hester et al.
- Affiliation:
- AAP · Netherlands
Abstract
A 27-year-old male chimpanzee (Pan troglodytes verus) developed signs of thrombotic thrombocytopenic purpura (TTP). ADAMTS13 deficiency appeared to be the cause of disease. After treatment with high-dose prednisone, haematological values and clinical signs recovered. This is the first description of spontaneous TTP associated with ADAMTS13 deficiency in a non-human primate.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28547839/