Peer-reviewed veterinary case report
Thyroid and kidney health in cats after low-dose radioiodine treatment
By Finch, N C et al.·Published in The Journal of small animal practice·2019·Bristol Veterinary School, United Kingdom·View original on PubMed →
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Original publication title: Thyroid and renal function in cats following low-dose radioiodine (111Mbq) therapy.
- Species:
- cat
Plain-English summary
A group of hyperthyroid cats received low-dose radioiodine therapy to treat their condition. Over the next year, 63% of the cats returned to normal thyroid function, but 25% developed overt hypothyroidism, which can affect kidney function. Some of these cats showed early signs of declining kidney health that were only detectable through specific tests. Overall, low-dose radioiodine therapy was effective for most cats, but regular monitoring of thyroid and kidney function is important after treatment to catch any potential issues early.
People also search for: cat hyperthyroidism treatment · low-dose radioiodine for cats · cat kidney function after thyroid treatment
Abstract
OBJECTIVES: To describe the effect of low-dose (111MBq) radioiodine therapy on thyroid and renal function in hyperthyroid cats over a 12-month follow-up period. MATERIALS AND METHODS: Client-owned hyperthyroid cats underwent low-dose radioiodine therapy and were followed-up for 12 months. Immediately before radioiodine treatment, and at 1, 6 and 12 months afterwards, total thyroxine, thyroid stimulating hormone, serum creatinine and glomerular filtration rate were measured. RESULTS: Fifteen of the 24 (63%) cats achieved euthyroidism following low-dose radioiodine treatment. The incidence of overt hypothyroidism was six of 24 (25%) cats. Of the six cats developing overt hypothyroidism, three had decreased renal function, with decreased glomerular filtration rate preceding azotaemia in two of these individuals. Transient overt or subclinical hypothyroidism before restoration of euthyroidism was not observed. CLINICAL SIGNIFICANCE: Low-dose radioiodine is effective treatment for hyperthyroidism in most cats but overt hypothyroidism may develop in some. Concurrent early decline in renal function may only be detected by measuring glomerular filtration rate rather than serum creatinine in some cats. Monitoring following radioiodine treatment should include total thyroxine and thyroid stimulating hormone and measurement of glomerular filtration rate should be considered in non-azotaemic cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31328277/