Peer-reviewed veterinary case report
Dog with thyroid carcino-sarcoma treated by surgery and radiotherapy
By Giuliano, Antonio et al.·Published in Journal of the South African Veterinary Association·2013·Veterinary Referral Cancer and Critical Care, United Kingdom·View original on PubMed →
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Original publication title: Thyroid carcino-sarcoma in a dog.
- Species:
- dog
Plain-English summary
A male greyhound was diagnosed with a thyroid tumor called carcino-sarcoma after tests showed abnormal cells. The vet performed surgery and used radiation therapy, which successfully controlled the tumor in the neck area. However, additional chemotherapy treatments did not stop the cancer from spreading to other parts of the body. Sadly, the dog lived for seven months after the diagnosis. This case highlights that while surgery and radiation can be effective, chemotherapy may not help prevent the cancer from returning or spreading.
People also search for: greyhound thyroid cancer treatment · dog thyroid tumor surgery · dog cancer chemotherapy effectiveness
Abstract
An adult male greyhound was diagnosed with a thyroid carcino-sarcoma by means of histopathology and positive immuno-histochemistry staining for cytokeratin and vimentin. Surgery and radiotherapy of the area were successful in local tumour control. Adjuvant chemotherapy was recommended to treat and prevent further metastasis. The use of carboplatin, metronomic cyclophosphamide chemotherapy and toceranib failed to control the progression of distant metastasis. The survival time was seven months from the time of diagnosis. This is the eighth case of carcino-sarcoma of the thyroid documented in veterinary medicine and the first one treated with a multimodal approach based on surgery, radiotherapy and chemotherapy. As documented in human medicine, chemotherapy appeared to be ineffective to prevent or delay the progression of the metastatic disease in this case.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23718201/