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Peer-reviewed veterinary case report

Dog with rare thyroid tumor causing pain when swallowing and lung

By Grubor, B & Haynes, J S·Published in Veterinary pathology·2005·Department of Veterinary Pathology, United States·View original on PubMed

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Original publication title: Thyroid carcinosarcoma in a dog.

Species:
dog

Plain-English summary

A mixed breed male dog developed pain when swallowing that lasted for a week. A vet found a lump in his neck and discovered that the cancer had spread to his lungs. The lump was surgically removed, and tests confirmed it was a rare type of thyroid cancer called carcinosarcoma. This case is notable because it was the first time specific cell markers were used to confirm the diagnosis in dogs. The dog received treatment, but the outcome details were not provided.

People also search for: dog swallowing pain · thyroid cancer in dogs · mixed breed dog neck lump treatment

Abstract

An adult male mixed breed dog developed pain, on swallowing, that lasted for 1 week. Physical exam and radiographs revealed a subcutaneous mass in the cervical area and three metastatic nodules in the lung. The cervical mass was surgically removed and fixed in 10% buffered formalin. Histopathologic diagnosis was carcinosarcoma supported by positive immunohistochemistry (IHC) results for cytokeratin and vimentin. IHC for thyroglobulin proved that the tissue of origin was the thyroid gland. This is the fifth canine case of thyroid carcinosarcoma to be documented, but the first one to be confirmed by specific cell markers. It is an extremely rare neoplasm that also occurs in people.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15657278/