Peer-reviewed veterinary case report
Thyroid test with human hormone in healthy and sick cats
By van Hoek, Ingrid M et al.·Published in Journal of feline medicine and surgery·2010·Department of Medicine and Clinical Biology of Small Animals·View original on PubMed →
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Original publication title: Thyroid stimulation with recombinant human thyrotropin in healthy cats, cats with non-thyroidal illness and in cats with low serum thyroxin and azotaemia after treatment of hyperthyroidism.
- Species:
- cat
Plain-English summary
A group of healthy cats and cats with health issues were tested to see how their thyroids responded to a hormone called recombinant human thyrotropin (rhTSH). The healthy cats showed a significant increase in thyroid hormone levels after the treatment, while the cats that had low thyroid hormone levels after treatment for hyperthyroidism did not respond as well. This suggests that rhTSH can help veterinarians determine if a cat's low thyroid hormone levels are due to treatment effects or other health problems. Understanding this can guide better treatment decisions for cats with thyroid issues.
People also search for: cat thyroid hormone test · low thyroid in cats treatment · hyperthyroidism treatment in cats
Abstract
This study investigated the recombinant human thyrotropin (rhTSH) stimulation test in healthy cats (group 1), cats with non-thyroidal illness (group 2) and cats with low serum total T(4) (TT(4)) and azotaemia after (131)I treatment (group 3). Serum TT(4) responses and thyroidal pertechnetate uptake after administration of 25 microg rhTSH IV were assessed. Baseline serum TT(4) was significantly lower in group 3 compared with group 1, but not between other group pairs. Serum TT(4) increased significantly in groups 1 and 2 but not in group 3 after rhTSH administration. Post-rhTSH serum TT(4) concentrations differed significantly between groups 1 and 3 and groups 2 and 3, but not between groups 1 and 2. Thyroid/salivary gland uptake ratio (T/S uptake ratio) differed only significantly between groups 1 and 3. Stimulation with rhTSH is valuable to differentiate euthyroidism from iatrogenic hypothyroidism in cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19783190/