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Peer-reviewed veterinary case report

Titanocene difluorides with improved cytotoxic activity.

Journal:
Inorganic chemistry
Year:
2010
Authors:
Eger, Silvia et al.
Affiliation:
Fachbereich Chemie and Konstanz Research School Chemical Biology · Germany

Abstract

Titanocene difluorides can be obtained by halide metathesis of the respective titanocene dichlorides with trimethyltin fluoride (Me(3)SnF), giving access to a new class of cytotoxic active substances. Furthermore, an improved method for the synthesis of diaryl-substituted titanocene dichlorides is presented.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20055428/