Peer-reviewed veterinary case report
Topical tacrolimus treats discoid lupus and pemphigus in dogs
By Griffies, Joel D et al.·Published in Journal of the American Animal Hospital Association·2004·Animal Dermatology Clinic, United States·View original on PubMed →
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Original publication title: Topical 0.1% tacrolimus for the treatment of discoid lupus erythematosus and pemphigus erythematosus in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with skin problems, specifically discoid lupus erythematosus (DLE) and pemphigus erythematosus (PE), were treated with a topical medication called tacrolimus. After eight weeks of treatment, most of the dogs showed improvement in their skin lesions, and some were able to stop taking other medications without any negative side effects. This suggests that tacrolimus can be an effective option for managing these conditions in dogs.
People also search for: dog skin problems treatment · tacrolimus for dogs · discoid lupus in dogs · pemphigus in dogs treatment
Abstract
Topical 0.1% tacrolimus was used for treatment of localized lesions associated with 10 cases of discoid lupus erythematosus (DLE) and two cases of pemphigus erythematosus (PE) either as a sole therapy (n=2) or as an adjunctive treatment (n=10). Eight of 10 dogs with DLE and both dogs with PE were improved following 8 weeks of topical application. In six of the eight dogs that improved, other medications were discontinued. No adverse effects in clinical or laboratory parameters were noted throughout the study.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14736903/