Peer-reviewed veterinary case report
Platelet-rich plasma heals large skin wound from clotting problem
By Tae‐Ho Chung et al.·Published in Irish Veterinary Journal·2015·View original on Semantic Scholar →
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Original publication title: Topical allogeneic platelet-rich plasma treatment for a massive cutaneous lesion induced by disseminated intravascular coagulation in a toy breed dog
- Species:
- dog
Plain-English summary
A 2-year-old female miniature Pinscher was brought to the vet after experiencing vomiting, lethargy, and developing large skin lesions on her hip and tail. She was diagnosed with acute pancreatitis, which caused her symptoms and led to serious skin issues. To help heal her wounds, the vet used a special treatment called allogeneic platelet-rich plasma (PRP), which promotes skin healing. After about a month of treatment, the dog's skin lesions showed significant improvement and healed completely.
People also search for: dog vomiting and lethargy · miniature Pinscher skin lesions treatment · acute pancreatitis in dogs · platelet-rich plasma for dog wounds
Abstract
A 2-year-old intact female miniature Pinscher weighing 1.7 kg with a body condition score of 2/5 was presented for acute vomiting, lethargy for 2 days, and large petechial skin lesions on the hip region including the tail. Acute pancreatitis was diagnosed by clinical signs, strong positive cPLI test, laboratory test and ultrasound appearance. While the clinical signs associated with acute pancreatitis had improved in 3–5 days, lesion of petechial appeared on the left hip region 7 days after the presentation, with a fast progression into a necrotic tissue along the left side hip. Allogenic platelet rich plasma (PRP) with Weibrich and Kleis method was administered to promote skin healing and regeneration. Gradual and complete improvement in the dog’s wound lesions was noted approximately 1 month after applying allogeneic topical PRP. In this case report, allogeneic PRP was applied to a large regional cutaneous defect caused by coagulopathy induced by acute pancreatitis. Topical application of PRP in this case was unique in that allogeneic PRP was used instead of autologous PRP for the first time in cutaneous soft-tissue wound management in the veterinary medical field.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/25763181