Peer-reviewed veterinary case report
Topical EDTA after corneal treatment for dog eye calcium buildup
By Anastassiadis, Zoe et al.·Published in Veterinary ophthalmology·2022·Veterinary Ophthalmic Referrals, Australia·View original on PubMed →
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Original publication title: Topical Ethylenediaminetetraacetic acid (EDTA) administration following corneal diamond burr keratotomy for calcareous corneal degeneration in canines.
- Species:
- dog
Plain-English summary
A 14-year-old small terrier was treated for corneal ulcers caused by calcareous corneal degeneration, a condition that can lead to vision problems. After a diamond burr keratotomy (a surgical procedure to smooth the cornea), the dog received topical Ethylenediaminetetraacetic acid (EDTA) to help with healing. While some dogs experienced a recurrence of ulcers, those that were retreated with a second surgery and continued EDTA treatment showed no further issues. Overall, using EDTA after surgery significantly lowered the chances of the corneal ulcers coming back.
People also search for: dog corneal ulcer treatment · small terrier eye problems · EDTA for dog eye issues
Abstract
OBJECTIVE: To evaluate the outcomes of canine patients diagnosed with corneal ulceration associated with presumed calcareous corneal degeneration (CCD) that were treated with diamond burr keratotomy (DBK) and ongoing postoperative topical 3% or 4% Ethylenediaminetetraacetic acid (EDTA). PROCEDURES: Retrospective assessment of CCD cases treated with ongoing topical EDTA following DBK between 2011 and 2020 at Veterinary Ophthalmic Referrals. Descriptive statistics of the study population were assessed, and a survival analysis was performed using R statistical software. RESULTS: A total of 51 eyes from 41 dogs were assessed, with small terrier breeds overrepresented (27/41, 65.9%). Median age of dogs at the time of diagnosis was 14.3 years (range 8-17.2 years). Following DBK, the median time to commencement of topical EDTA was 11 days (range 0-28 days). Cases were followed for a median duration of 216 days (range 42-1379 days). Corneal ulceration recurred in 7/51 (13.7%) eyes at a median duration of 80 days (range 63-156 days). The probability of recurrence of corneal ulceration associated with CCD at 12 months was 15.6% (95% CI: 4.1-25.7%). A second DBK procedure followed by ongoing topical EDTA was performed in 4/7 (57.1%) of the recurred eyes. These retreated eyes had no further recurrence recorded and a median follow-up time of 401 days (range 120-858 days). CONCLUSION: Ongoing topical EDTA following DBK is an effective adjunct treatment method for CCD with reduced rates of recurrence of CCD-associated corneal ulceration when compared to published rates of recurrence when treated with DBK alone.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35006635/