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Peer-reviewed veterinary case report

Topiramate attenuates a transient learning deficit after lesions inducing intracerebral hemorrhage.

Journal:
Psychological reports
Year:
2007
Authors:
McDaniel, William F et al.
Affiliation:
Department of Psychology · United States
Species:
rodent

Abstract

28 male Long-Evans rats prepared with lesions of the middle cerebral artery displayed deficits in spatial navigational learning in a simple version of the Morris Water Maze task not seen in animals prepared with the same injury but administered 4 treatments with topiramate after surgery.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17451019/