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Peer-reviewed veterinary case report

Towards a genetic AIDS vaccine.

Journal:
Retrovirology
Year:
2009
Authors:
Bordería, Antonia V & Berkhout, Ben
Affiliation:
Department of Medical Microbiology · Netherlands

Abstract

We discuss a recent Nature Medicine publication by Philip Johnson and co-workers (Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. Nat. Med. 2009, 15: 901-906) in which an effective HIV-1 vaccine was designed that is based on gene therapy. The introduced gene produces an antibody-like immunoadhesin in the blood that neutralizes the virus.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19835599/