Peer-reviewed veterinary case report
Toxoplasma gondii: congenital transmission in a hamster model.
- Journal:
- Experimental parasitology
- Year:
- 2009
- Authors:
- Freyre, A et al.
- Affiliation:
- Laboratorio de Toxoplasmosis
- Species:
- rodent
Abstract
The objective of the research was to test the hamster for a model of transmission of congenital toxoplasmosis. A non-invasive method for the diagnosis of pregnancy in hamsters was designed, with a specificity and a sensitivity of 70.2 and 94.7%, respectively (n=168). Of 32 females with a chronic toxoplasma infection, 3 transmitted Toxoplasma congenitally during their first pregnancy, but not during the subsequent pregnancy. Congenital transmission rates of infections initiated during pregnancy with 2 stages of 2 strains of Toxoplasma were in the range of 33 to 100% of the 76 females inoculated. Only 1 of 17 females transmitted the parasite exclusively via milk. It was concluded that the hamster is a promising species for a model of transmission of congenital toxoplasmosis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19217907/