Peer-reviewed veterinary case report
Dog with brain problems from toxoplasmosis, distemper
By Moretti, Leandro d'Arc et al.·Published in Revista do Instituto de Medicina Tropical de Sao Paulo·2006·Serviç, Brazil·View original on PubMed →
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Original publication title: Toxoplasma gondii genotyping in a dog co-infected with distemper virus and ehrlichiosis rickettsia.
- Species:
- dog
Plain-English summary
A 3-year-old dog was brought in showing severe neurological problems, which included symptoms like seizures and coordination issues. The dog was found to be co-infected with three serious diseases: toxoplasmosis, distemper, and ehrlichiosis. The vet diagnosed these infections through blood tests and clinical signs. Unfortunately, the dog's condition was complicated due to the immunosuppressive effects of these infections. The report highlights the importance of recognizing such co-infections, especially in areas where these diseases are prevalent.
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Abstract
This paper reports a toxoplasmosis, ehrlichiosis and distemper co-infection in a dog with an exuberant neuropathological clinical picture. Primary involvement was discussed based on information collected in the analysis of the clinical case, such as neurological impairment, epidemiological data, poor immunoprophylactic scheme of the dog affected and the role of these diseases on immunosuppression. Canine distemper and ehrlichiosis were diagnosed based on epidemiologic data, clinical signs, hematological and cytological evaluation. Toxoplasma gondii was isolated and genetically characterized as Type I using restriction analysis (RFLP) with SAG-2 genes. Immunosuppression features of both dogs and human beings are discussed, as well as implications on animal and public health. This is the first report on toxoplasmosis, ehrlichiosis and distemper co-infection in a dog in Brazil, associated with genotyping determination of the T. gondii strain involved.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17221136/