Peer-reviewed veterinary case report
Relapsing toxoplasmosis in two cats with intestinal inflammation
By Peterson, J L et al.·Published in Journal of the American Veterinary Medical Association·1991·Department of Small Animal Medicine, United States·View original on PubMed →
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Original publication title: Toxoplasmosis in two cats with inflammatory intestinal disease.
- Species:
- cat
Plain-English summary
A 5-year-old domestic shorthair cat with chronic intestinal inflammation was experiencing recurring symptoms despite treatment. The vet discovered that the cat's issues were actually due to a relapse of toxoplasmosis, a parasitic infection, likely caused by the immunosuppressive medications being used. After starting treatment with clindamycin, the cat's condition improved, and the toxoplasmosis was resolved. Another cat with similar intestinal disease showed signs of active toxoplasmosis through blood tests but did not exhibit symptoms; clindamycin also helped reduce the infection in this case.
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Abstract
Lymphocytic-plasmacytic enteritis, a chronic inflammatory intestinal disease, was diagnosed in 2 cats. In 1 cat, recurrence of clinical signs after initiating treatment was attributed to relapse of the inflammatory intestinal disease, but was found to be attributable to relapsing toxoplasmosis secondary to immunosuppressive drug therapy. Treatment with clindamycin resolved the recurrent toxoplasmosis. In the second cat, clinical signs of toxoplasmosis did not develop, but serologic testing yielded evidence of active toxoplasmosis. Treatment with clindamycin caused the titers to decrease. Relapsing toxoplasmosis may be responsible for apparent resistance to treatment in cats for inflammatory intestinal disease being treated with immunosuppressive drugs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1917660/