Peer-reviewed veterinary case report
How transepidermal water loss shows dog skin barrier damage
By Shimada, Kenichiro et al.·Published in The Journal of veterinary medical science·2008·Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: Transepidermal water loss (TEWL) reflects skin barrier function of dog.
- Species:
- dog
Plain-English summary
A study found that when the outer layer of skin was removed from healthy dogs, it led to increased water loss through the skin, indicating a weakened skin barrier. This was measured using a special device that tracks how much water evaporates from the skin. The more the outer layer was damaged, the more water was lost, showing that a healthy skin barrier is crucial for keeping moisture in. This information can help veterinarians assess skin health in dogs and guide treatment for skin problems.
People also search for: dog skin problems · why is my dog’s skin dry · dog skin barrier treatment
Abstract
The correlation between skin barrier function and transepidermal water loss (TEWL) was evaluated in dogs. Stratum corneum (SC) of 10 healthy dogs was removed by tape stripping (TS), which decreased the corneal layer to allow for permeation of fluorescent dye into skin. TEWL of damaged skin was measured with the closed-chamber-type TEWL analyzer, CC-01. The frequency of TS was directly related to the decrease of SC and the increased permeation of fluorescent dye, and TEWL increased with increasing impairment of skin barrier function. The results suggest that increased TEWL reflects impaired canine skin barrier function.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18772562/