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Peer-reviewed veterinary case report

Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys.

Journal:
Journal of virology
Year:
2013
Authors:
Ho, Carrie et al.
Affiliation:
Human Vaccine Institute.

Abstract

Natural hosts of simian immunodeficiency virus (SIV), African green monkeys (AGMs), rarely transmit SIV via breast-feeding. In order to examine the genetic diversity of breast milk SIV variants in this limited-transmission setting, we performed phylogenetic analysis on envelope sequences of milk and plasma SIV variants of AGMs. Low-diversity milk virus populations were compartmentalized from that in plasma. However, this compartmentalization was transient, as the milk virus lineages did not persist longitudinally.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23926337/