Peer-reviewed veterinary case report
Maltese puppy's temporary kidney problem after common meds
By Ahn, Jin-Ok et al.·Published in Journal of the American Animal Hospital Association·2019·From the Department of Veterinary Internal Medicine, South Korea·View original on PubMed →
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Original publication title: Transient Fanconi Syndrome After Treatment with Firocoxib, Cefadroxil, Tramadol, and Famotidine in a Maltese.
- Species:
- dog
Plain-English summary
A 10-month-old Maltese was brought to the vet because he was lethargic, not eating, vomiting, and losing weight. After treatment with a combination of medications, he developed transient Fanconi syndrome, which caused him to lose important nutrients in his urine. The vet provided supportive care, including IV fluids and nutritional supplements, and after two months, the dog fully recovered with no more signs of the condition. This case highlights the potential kidney issues that can arise from certain medication combinations.
People also search for: Maltese vomiting and weight loss · Fanconi syndrome in dogs · dog kidney problems treatment
Abstract
Fanconi syndrome is a renal proximal tubulopathy characterized by excessive urinary loss of glucose, amino acids, several electrolytes, and bicarbonate. Here, we report the case of transient Fanconi syndrome in a dog following administration of firocoxib, cefadroxil, tramadol, and famotidine. A 10 mo old Maltese was presented with lethargy, anorexia, vomiting, and weight loss. Transient Fanconi syndrome without azotemia was associated with firocoxib, cefadroxil, tramadol, and famotidine treatment. The dog received supportive care including IV fluids, gastroprotectants, and oral nutritional supplements. Two months after initial diagnosis and treatment, the dog showed complete resolution of glucosuria and aminoaciduria. The unique features of Fanconi syndrome in this case emphasize the potential renal tubular toxicity of this widely used multiple-drug combination.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31525093/