Peer-reviewed veterinary case report
Weight loss and glucose in urine in Quarter horses - what is Fanconi
By Ohmes, Cameon M et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2014·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Transient Fanconi syndrome in Quarter horses.
- Species:
- horse
Plain-English summary
Two Quarter horses were experiencing weight loss and tests showed they had sugar in their urine, normal blood sugar levels, and a slight imbalance in their body chemistry, which suggested a problem with their kidneys. Additional tests revealed they also had high levels of certain amino acids and lactic acid in their urine, confirming a condition known as Fanconi syndrome, which affects kidney function. Fortunately, both horses received supportive treatment and made a full recovery. This case is notable as it is the first documented instance of acquired Fanconi syndrome in horses.
Abstract
Two Quarter horses with weight loss had glucosuria, euglycemia, and a mild metabolic acidosis suggesting a proximal renal tubular defect. Further testing revealed transient generalized aminoaciduria, lactic aciduria, and glucosuria, indicating Fanconi syndrome. Both horses recovered with supportive therapy. This is the first report of acquired Fanconi syndrome in horses.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24489393/