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Peer-reviewed veterinary case report

Transmission of different strains of Plasmodium cynomolgi to Aotus nancymaae monkeys and relapse.

Journal:
The Journal of parasitology
Year:
2009
Authors:
Collins, William E et al.
Affiliation:
National Center for Zoonotic · United States

Abstract

Forty-four splenectomized Aotus nancymaae monkeys were infected with 6 different strains of Plasmodium cynomolgi, 11 via trophozoites and 33 via sporozoites. Sporozoites from Anopheles dirus, Anopheles freeborni, Anopheles gambiae, Anopheles maculatus, and Anopheles stephensi resulted in prepatent periods ranging from 9 to 39 days (median of 15 days). Importantly, relapse was demonstrated in 5 of 5 sporozoite-induced infections with the Rossan strain following treatment with chloroquine.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18788885/