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Peer-reviewed veterinary case report

Dog with mitral valve disease dies from heart attack caused by blood

By Seki, Y et al.·Published in The Journal of veterinary medical science·1998·Department of Veterinary Pathology, Japan·View original on PubMed

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Original publication title: Transmural myocardial infarction caused by thromboembolism associated with mitral insufficiency in a dog.

Species:
dog

Plain-English summary

A 10-year-old dog with a history of heart problems suddenly died. The cause was found to be a heart attack due to a blood clot blocking a major artery, which was linked to thickening of the mitral valve from a condition called mitral insufficiency (where the valve doesn't close properly). The vet discovered that the blood clot had formed in the heart and then traveled to block the artery, leading to the heart attack. Unfortunately, despite the investigation, the dog could not be saved.

People also search for: dog heart attack symptoms · mitral insufficiency in dogs · sudden death in older dogs

Abstract

A 10-year-old dog, which had been treated for mitral insufficiency, died suddenly. Transmural myocardial infarction secondary to thromboembolic occlusion of the subsinuosal interventricular branch of the left circumflex artery was noted in the posterior lower half of the left ventricular wall, involving the interventricular septum and a part of right ventricular wall. The mitral valve leaflets were markedly thickened (valvular endocardiosis). These were a patchy area of jet lesion and several mural thrombi on the left-atrial endocardium. The embolus in the subsinuosal interventricular branch was composed of mostly platelets and fibrin, showing the same histologic features as those of the mural thrombi on the left-atrial endocardium. From these findings, it was concluded that dislodgement of part of the mural thrombi on the left-atrial endocardium caused thromboembolism of the subsinuosal interventricular branch.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9673948/