Peer-reviewed veterinary case report
Transplantation of adipose derived mesenchymal stem cells for acute thoracolumbar disc disease with no deep pain perception in dogs.
- Journal:
- Journal of veterinary science
- Year:
- 2016
- Authors:
- Kim, Yongsun et al.
- Affiliation:
- Research Institute for Veterinary Science and College of Veterinary Medicine · South Korea
- Species:
- dog
Abstract
Thirty-four dogs with no deep pain perception due to acute thoracolumbar intervertebral disc disease underwent decompression surgery within 1 week of diagnosis. All dogs underwent hemilaminectomy. Adipose derived mesenchymal stem cells (AD-MSCs) were transplanted into the injured spinal cord parenchyma for the AD-MSCs transplant dogs. Long-term outcome was evaluated at the end of the follow-up period (> 6 months). AD-MSCs combination treatment showed better recovery outcomes compared to decompression surgery alone. These results indicate that this stem cell therapy is a potential therapeutic strategy to overcome the limitations of treatment for spinal cord injury in clinical medicine.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27051350/