Peer-reviewed veterinary case report
Closing moderate to large patent ductus arteriosus in dogs
By Hildebrandt, Nicolai et al.·Published in Journal of veterinary internal medicine·2022·Small Animal Clinic (Internal Medicine), Germany·View original on PubMed →
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Original publication title: Transvenous embolization of moderate to large patent ductus arteriosus in dogs using the Amplatzer vascular plug II.
- Species:
- dog
Plain-English summary
A group of 19 dogs with a heart condition called patent ductus arteriosus (PDA), which causes abnormal blood flow, underwent a new treatment using a device called the Amplatzer vascular plug II. Most dogs had successful closure of the PDA after one or two procedures, with 94.7% achieving complete closure within 24 hours. One dog had a moderate residual shunt but eventually closed completely after three months. This method proved to be safe and effective for treating this heart issue in dogs.
People also search for: dog heart murmur treatment · patent ductus arteriosus in dogs · Amplatzer vascular plug for dogs
Abstract
BACKGROUND: Catheter-based occlusion of patent ductus arteriosus (PDA) can be performed using different devices. Transvenous embolization using the Amplatzer vascular plug II (AVP-II) has been studied in humans, but it has not been described in dogs. OBJECTIVE: Evaluate the feasibility and success of transvenous embolization of PDA using the AVP-II in dogs. ANIMALS: Nineteen client-owned dogs with left-to-right shunting PDA, with minimal ductal diameter >2.5 mm. METHODS: Prospective observational study using AVP-II with transvenous access for PDA closure in dogs. RESULTS: Angiography showed a conical ductus with a long (n = 17) or short (n = 2) ampulla. The minimal diameter of the duct was 4.34 ± 1.11 mm, and the maximal diameter of the ampulla was 13.18 ± 3.47 mm. Technical success was achieved in 18 of the 19 (94.7%) patients after the first intervention and in all 19 (100%) patients after the second intervention. Postrelease angiography documented complete occlusion of the PDA in 10 of 19 (52.6%) dogs. Mild flow acceleration or stenosis of the left pulmonary artery was found in 6 and 1 of the 17 analyzed cases, respectively, by Doppler examination. The closure rate 24 hours after intervention was 94.7% (18/19). The remaining dog had a moderate residual shunt, and delayed complete closure after 3 months led to a 100% closure rate. CONCLUSION AND CLINICAL IMPORTANCE: The AVP-II is a safe and effective device for transvenous embolization in dogs with moderate to large PDA.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34914141/