Peer-reviewed veterinary case report
IV nitroglycerin treatment for heart failure in dogs with valve
By Achiel, Ron et al.·Published in Journal of the American Animal Hospital Association·2020·From the Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Treatment of Congestive Heart Failure with Intravenous Nitroglycerin in Three Dogs with Degenerative Valvular Disease.
- Species:
- dog
Plain-English summary
Three dogs with degenerative mitral valve disease were brought to the vet for breathing problems and were diagnosed with left congestive heart failure. In addition to their usual heart failure treatments, they received intravenous nitroglycerin, which helped improve their condition without any side effects. This treatment is a new approach in veterinary medicine, and while it showed promise, more research is needed to confirm its safety and effectiveness.
People also search for: dog breathing problems treatment · congestive heart failure in dogs · nitroglycerin for dogs heart disease
Abstract
We described the use of IV nitroglycerin as adjunctive therapy in three canine patients with left congestive heart failure secondary to degenerative mitral valve disease. All three dogs were admitted for signs of respiratory distress and all were determined to be in left congestive heart failure by history, exam findings, thoracic radiographs, and echocardiography. In addition to standard therapy for left congestive heart failure, IV nitroglycerin was administered as a constant rate infusion at a dose of 1-6 mcg/kg/min. No adverse events attributable to the drug were noted. This is the first reported use of IV nitroglycerin in clinical veterinary patients. Further studies are warranted to investigate the safety, efficacy, and optimal dosing of IV nitroglycerin infusions in dogs with left congestive heart failure.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31715115/