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Peer-reviewed veterinary case report

Milbemycin oxime stops esophageal spirocercosis in dogs

By Kelly, P J et al.·Published in Veterinary parasitology·2008·Ross University School of Veterinary Medicine·View original on PubMed

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Original publication title: Treatment of esophageal spirocercosis with milbemycin oxime.

Species:
dog

Plain-English summary

Six mixed breed dogs were treated for a parasitic infection called spirocercosis, which can cause serious issues in the esophagus. They received a medication called milbemycin oxime over several weeks, and within a few days to weeks, they stopped shedding the parasite's eggs. All dogs showed improvement, with esophageal nodules disappearing within a few months and no signs of the infection remaining in follow-up tests. This suggests that milbemycin oxime could be an effective treatment for this condition.

People also search for: dog esophageal infection treatment · spirocercosis in dogs · milbemycin oxime for dogs

Abstract

Six medium sized mixed breed dogs treated with milbemycin oxime (11.5mg on days 0, 7 and 28 and then monthly) stopped shedding Spirocerca lupi ova after 3-44 days. There was no evidence of subsequent shedding in repeated tests (about 5/dog) carried out from 31 to 133 days after initiation of treatment. Esophageal nodules disappeared in all dogs within 95-186 days and radiographic signs resolved within 85-127 days in the five dogs that were studied. This preliminary data shows milbemycin oxime deserves further evaluation for the treatment of spirocercosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18644677/