Peer-reviewed veterinary case report
Treating high blood pressure in cats with skin gel amlodipine
By Helms, Scott Roderick·Published in Journal of the American Animal Hospital Association·2007·Unifour Veterinary Referrals, United States·View original on PubMed →
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Original publication title: Treatment of feline hypertension with transdermal amlodipine: a pilot study.
- Species:
- cat
Plain-English summary
A group of six cats with high blood pressure was treated with a medication called amlodipine, first given orally and then through the skin. The oral form successfully lowered their blood pressure, but after switching to the transdermal version, their blood pressure increased slightly. This suggests that while transdermal amlodipine may not be as effective as the oral form for managing hypertension in cats, more research is needed to find the right dosage and effectiveness.
People also search for: cat high blood pressure treatment · transdermal amlodipine for cats · feline hypertension medication
Abstract
This prospective study evaluated transdermal amlodipine for the control of hypertension in six cats. Cats were treated with oral amlodipine until blood pressures decreased to <180 mm Hg. They were maintained on this dose for 7 days and then administered identical doses of transdermal amlodipine for 7 days. Oral amlodipine decreased pressure by a median of 73 mm Hg, which subsequently increased by 20 mm Hg after 7 days of transdermal amlodipine. Plasma concentrations of amlodipine were measured after oral and transdermal dosing. Additional studies are needed to determine dosing, pharmacokinetics, and efficacy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17473021/