Peer-reviewed veterinary case report
Treatment of fibroadenomatosis in female cats with aglepristone
By Jurka, P & Max, A·Published in The Veterinary record·2009·Faculty of Veterinary Medicine·View original on PubMed →
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Original publication title: Treatment of fibroadenomatosis in 14 cats with aglepristone - changes in blood parameters and follow-up.
- Species:
- cat
Plain-English summary
Fourteen female cats with a condition called fibroadenomatosis (a type of breast tissue overgrowth) were treated with a medication called aglepristone. Most of the cats showed complete improvement in their symptoms about 4 weeks after starting treatment, and their blood tests returned to normal. After treatment, six of the cats were bred, and four had healthy litters without any signs of fibroadenomatosis. The other eight cats had surgery to remove their ovaries and uterus shortly after treatment.
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Abstract
Fourteen female cats with fibroadenomatosis were treated with aglepristone, and the effectiveness of the treatment and its effect on selected haematological and blood chemistry parameters were studied. The cats were monitored for 12 months after the end of the treatment. Complete remission of the clinical signs was achieved on average 3.9 weeks after the treatment began; the success of the treatment confirmed the clinical diagnosis of fibroadenomatosis. During the course of the treatment the cats' haematological parameters returned to normal. In cats that had previously been treated with long-acting medroxyprogesterone acetate, treatment with aglepristone for five weeks was recommended. Cases of fibroadenomatosis reappearing after a few months should be regarded as new disease rather than a relapse. Six cats were subsequently mated and four gave birth to one or more litters; all the pregnancies proceeded normally with no clinically evident fibroadenomatosis. The other eight cats underwent ovariohysterectomy soon after the aglepristone treatment was completed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19946126/