Peer-reviewed veterinary case report
Dog treated with IV lipid for severe ibuprofen poisoning
By Bolfer, Luiz et al.·Published in Journal of the American Animal Hospital Association·2014·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Treatment of ibuprofen toxicosis in a dog with IV lipid emulsion.
- Species:
- dog
Plain-English summary
A 3-year-old spayed female mixed-breed dog was brought in after accidentally eating a large amount of ibuprofen, which is a common pain reliever for humans. She initially showed signs of excessive drooling but quickly became unresponsive and fell into a coma. The veterinarian provided supportive care and treated her with a special IV lipid emulsion, which helped her condition improve within a few hours. After three days of care, she was stable enough to go home.
People also search for: dog ibuprofen poisoning treatment · dog drooling and lethargy · IV lipid emulsion for dogs
Abstract
A 3 yr old spayed female mixed-breed dog weighing 19.4 kg was evaluated for ingestion of 1,856 mg/kg (180 tablets) of ibuprofen, a human formulated nonsteroidal anti-inflammatory drug (NSAID). At the time of presentation, the patient was alert and hypersalivating, but her mental status rapidly declined to obtunded, stuporous, and then comatose within 30 min of presentation. Initial treatment included supportive therapy with prostaglandin analogs and antiemetics. An IV lipid emulsion (ILE) was administered as a bolus, followed by a constant rate infusion. Clinical signs began to improve approximately 3 hr after completion of the lipid infusion. The patient required supportive care for 3 days before discharge. This case report demonstrates the use of ILE for treatment of ibuprofen toxicosis in a dog. ILE infusion may be a therapeutic option for patients with toxicosis due to lipid-soluble drugs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24446399/