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Peer-reviewed veterinary case report

Treatment of immune-mediated keratitis in dogs using eye

By Kim, Hyelin et al.·Published in Journal of veterinary science·2023·Department of Veterinary Clinical Sciences, South Korea·View original on PubMed

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Original publication title: Treatment of immune-mediated keratitis (IMMK) in dogs with immunosuppressants observed with spectral domain optical coherence tomography (SD-OCT).

Species:
dog
Canine GlaucomaBehaviour & energyDogs

Plain-English summary

Two dogs with cloudy eyes due to a condition called immune-mediated keratitis were treated with eye drops containing immunosuppressants. After a thorough eye exam, the dogs were given 0.03% tacrolimus ointment, which helped clear their corneas. However, the eye problems returned when the treatment was stopped. Continuous use of these eye drops is important to keep the eyes clear and prevent further scarring.

People also search for: dog cloudy eyes treatment · immune-mediated keratitis in dogs · tacrolimus for dog eye problems

Abstract

Two dogs presented with bilateral pattern-forming corneal opacity. Treatment with topical immunosuppressants was initiated after a complete ophthalmic examination. The response to treatment was assessed by analyzing serial images using slit-lamp biomicroscopy and spectral domain optical coherence tomography (SD-OCT). Both dogs responded to topical immunosuppressants; however, the lesions recurred once the treatment was abated or withdrawn. The most effective immunosuppressant in both dogs was 0.03% tacrolimus ointment. Early and continuous treatment with topical immunosuppressants may be necessary to improve corneal clarity and prevent scarring. SD-OCT could provide useful structural information regarding presumed immune-mediated keratitis and aid in monitoring treatment response.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38031645/