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Peer-reviewed veterinary case report

Fipronil spot-on treatment for cat Neotrombicula mite infestation

By Cadiergues, Marie C et al.·Published in Journal of feline medicine and surgery·2018·1 UDEAR, France·View original on PubMed

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Original publication title: Treatment of Neotrombicula species infestation in cats using a 10% (w/v) fipronil topical spot-on formulation: a pilot study.

Species:
cat
Skin & coatCats

Plain-English summary

A group of 15 cats with a skin infestation caused by Neotrombicula mites were treated with a topical fipronil solution. Over the course of the study, the treated cats showed significant improvement in their skin condition and reduced itching, while the untreated cats did not improve at all. By the end of the treatment period, the cats receiving fipronil had much lower parasite counts and less severe skin lesions, with no side effects reported. This suggests that fipronil is an effective and safe option for treating this type of mite infestation in cats.

People also search for: cat skin mites treatment · Neotrombicula infestation in cats · fipronil for cat skin problems

Abstract

Objectives Few data are available concerning therapeutic aspects of feline trombiculiasis. This study evaluated the efficacy of a 10% w/v fipronil-based spot-on solution in 15 cats with natural Neotrombicula species infestation. Methods Ten cats received 1 drop per affected site on day (D)0 and D14, with the rest of the 0.5 ml pipette applied on the skin between the shoulders. Five cats served as non-treated controls. Parasite score (0 = absent; 3 = severe, >10 parasites/zone) was assessed on D0, D14 and D28 on all animals. Skin lesions (SCORing Feline Allergic Dermatitis lesion severity scale [SCORFAD]) and investigator pruritus scale (IPS; 0 = cat comfortable, grooming like any normal cat; 4 = cat uncomfortable, pruritic all the time) were assessed on treated cats on the same days. Global assessment of efficacy, tolerance and ease of use (GAS; 1 = very poor; 5 = excellent) was assessed on D28. Results All the cats completed the study. Parasite scores of the control cats were maintained throughout the trial (mean &#xb1; SD: D0 4 &#xb1; 0.7, D14 3.2 &#xb1; 1.1 and D28 3.2 &#xb1; 0.4). In treated cats, SCORFAD (D0 3.2 &#xb1; 5.4, D14 1.1 &#xb1; 2.1 [ P <0.002] and D28 0.5 &#xb1; 1.3 [ P <0.002]), parasite (D0 3.9 &#xb1; 1.3, D14 1.2 &#xb1; 0.8 [ P <0.005] and D28 0.4 &#xb1; 0.5 [ P <0.005]) and IPS (D0 1 &#xb1; 1.2, D14 0.5 &#xb1; 1.1 [ P <0.05] and D28 0.3 &#xb1; 0.7 [ P <0.05]) scores significantly decreased throughout the trial. On D28, the GAS was 4.2 &#xb1; 0.9. There were no adverse effects from treatment. Conclusions and relevance The 10% w/v fipronil preparation appeared to be effective, safe and practical in the treatment of localised Neotrombicula species infestation in these cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28627284/