Peer-reviewed veterinary case report
Newly diagnosed diabetic cats have better remission with glargine
By Marshall, R D et al.·Published in Journal of feline medicine and surgery·2009·School of Veterinary Science, Australia·View original on PubMed →
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Original publication title: Treatment of newly diagnosed diabetic cats with glargine insulin improves glycaemic control and results in higher probability of remission than protamine zinc and lente insulins.
- Species:
- cat
Plain-English summary
A group of 24 newly diagnosed diabetic cats were treated with different types of insulin to see which worked best for controlling blood sugar levels. The cats received either glargine insulin, protamine zinc insulin, or lente insulin, along with a low carbohydrate diet. The results showed that the cats treated with glargine had better blood sugar control and all of them achieved remission, meaning their diabetes went into a state of non-activity. In contrast, fewer cats treated with the other insulins reached remission. This suggests that glargine insulin is the most effective option for newly diagnosed diabetic cats.
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Abstract
Glycaemic control and remission probabilities were compared in 24 newly diagnosed diabetic cats treated twice daily with either glargine, protamine zinc (PZI) or lente insulin and fed a low carbohydrate diet. After day 17, the probability of remission was substantially higher for cats with lower mean 12h blood glucose concentrations on day 17, irrespective of insulin type. Glargine-treated cats had lower mean 12h blood glucose concentrations on day 17 than PZI- or lente-treated cats, and all eight glargine-treated cats achieved remission compared to three PZI- and two lente-treated cats. The probability of remission was greater for cats treated with glargine than cats treated with PZI or lente insulin. In newly diagnosed diabetic cats, twice daily treatment with glargine provides better glycaemic control and higher probability of remission compared to twice daily treatment with PZI or lente insulin. Good glycaemic control soon after diagnosis is associated with increased probability of remission and should be the goal of insulin therapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19539509/