Peer-reviewed veterinary case report
Hemodialysis treatment for phenobarbital poisoning in dogs
By Basile, Jessica Kielb & Vigani, AlessioĀ·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)Ā·2020Ā·North Carolina State Veterinary HospitalĀ·View original on PubMed ā
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Original publication title: Treatment of phenobarbital intoxication using hemodialysis in two dogs.
- Species:
- dog
Plain-English summary
Two dogs became very sick after accidentally ingesting a dangerous amount of phenobarbital, which caused severe neurological issues and left them in a coma. Both dogs underwent a 3-hour hemodialysis treatment, which successfully removed the drug from their systems. By the end of the treatment, they were fully alert and showed no side effects. This case highlights that hemodialysis can be a safe and effective option for treating phenobarbital poisoning in dogs.
People also search for: dog phenobarbital overdose treatment Ā· dog coma recovery Ā· hemodialysis for dogs
Abstract
OBJECTIVE: To describe the use of hemodialysis in 2 dogs with severe clinical signs from phenobarbital intoxication. SERIES SUMMARY: Two dogs ingested a toxic dose of phenobarbital, leading to severe neurological dysfunction and a comatose state. Both dogs received a 3-hour session of hemodialysis with complete resolution of clinical signs and returned to normal mentation by the end of the therapy. No negative side effects occurred and phenobarbital concentrations returned to therapeutic range during treatment. NEW INFORMATION PROVIDED: This is the first report on the utility and safety of using hemodialysis for phenobarbital intoxication in dogs.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31975513/