Peer-reviewed veterinary case report
Treatment of skin lesions in cats with resistant sporotrichosis using
By Gremião, Idf et al.·Published in Australian veterinary journal·2011·Evandro Chagas Clinical Research Institute/Oswaldo Cruz Foundation (Fiocruz), Brazil·View original on PubMed →
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Original publication title: Treatment of refractory feline sporotrichosis with a combination of intralesional amphotericin B and oral itraconazole.
- Species:
- cat
Plain-English summary
A group of 26 cats with stubborn skin lesions caused by sporotrichosis (a fungal infection) that didn’t improve with oral itraconazole was treated with a combination of intralesional amphotericin B (an antifungal injected directly into the lesions) and continued oral itraconazole. After treatment, 22 of the cats showed significant improvement, with 16 completely cured. Some cats still had recurring lesions, but overall, this combination treatment proved effective for those struggling with this infection.
People also search for: cat skin lesions treatment · sporotrichosis in cats · antifungal treatment for cats
Abstract
OBJECTIVE To describe the use of intralesional amphotericin B in localised lesions for the treatment of 26 cats from Rio de Janeiro, Brazil, with sporotrichosis refractory to oral itraconazole. DESIGN Uncontrolled intervention study. METHOD The 26 cats in this study were diagnosed with sporotrichosis, confirmed by isolation of Sporothrix schenckii, and presented residual localised skin lesions refractory to treatment with oral itraconazole for a minimum period of 8 weeks. The animals received weekly applications of intralesional amphotericin B in conjunction with oral itraconazole. In cases of owner unavailability, a maximum of 2 weeks between the infiltrations was accepted. RESULTS Twenty-two (84.6%) of the 26 treated cats achieved clinical remission, 16 (72.7%) of which were cured, and in the remaining six (27.3%) the lesions recurred at the same site. Lack of clinical response was observed in one animal and three owners abandoned treatment. CONCLUSION The proposed therapeutic regimen is an adjunctive treatment option for cats with sporotrichosis presenting as residual skin lesions refractory to itraconazole.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21864307/