Peer-reviewed veterinary case report
Severe skin drug reactions in dogs treated with human IVIG
By Trotman, Tara K et al.·Published in Journal of the American Animal Hospital Association·2006·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Treatment of severe adverse cutaneous drug reactions with human intravenous immunoglobulin in two dogs.
- Species:
- dog
Plain-English summary
Two dogs developed severe skin reactions and other health issues after taking various medications. Traditional treatments weren't helping, so the veterinarians decided to try human intravenous immunoglobulin (IVIG), which is a treatment that helps the immune system. After receiving IVIG over two days, both dogs showed quick improvement in their skin and overall health. This suggests that IVIG could be a good option for other pets experiencing serious skin reactions to medications.
People also search for: dog skin reaction treatment · IVIG for dogs · severe skin problems in dogs · dog medication side effects · dog allergic reaction treatment
Abstract
Severe adverse cutaneous reactions were documented in two dogs with acute skin lesions and systemic signs after exposure to several oral and injectable drugs. Because of the high morbidity and mortality rates of many severe cutaneous drug reactions and a poor response to supportive care, wound management, and conventional immunosuppressive therapy, human intravenous immunoglobulin (IVIG) was infused on 2 consecutive days (1 g/kg per day) after informed consent was received. Human IVIG, with supportive care, resulted in rapid resolution of dermatological and systemic signs in both dogs; this treatment may be considered in other cases of severe cutaneous drug reactions.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16822772/