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Peer-reviewed veterinary case report

Dog with severe digoxin poisoning and heart disease

By Ward, D M et al.·Published in Journal of the American Veterinary Medical Association·1999·Department of Small Animal Clinical Sciences, United States·View original on PubMed

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Original publication title: Treatment of severe chronic digoxin toxicosis in a dog with cardiac disease, using ovine digoxin-specific immunoglobulin G Fab fragments.

Species:
dog

Plain-English summary

A 13-year-old mixed-breed dog with heart disease was brought in for severe digoxin poisoning after receiving too much of the medication. The veterinarian treated the dog with a special antibody therapy made from sheep, which helped to reverse the toxic effects of digoxin. Although the treatment was successful, the dog experienced some complications, including low magnesium levels and a reduction in the heart-strengthening effects of digoxin. Overall, the dog was able to recover from the digoxin toxicosis with appropriate care.

People also search for: dog digoxin poisoning treatment · heart disease in dogs · mixed-breed dog heart medication issues

Abstract

Severe digoxin toxicosis in a 13-year-old mixed-breed dog with dilated cardiomyopathy was successfully treated with i.v. administration of ovine digoxin-specific IgG Fab fragments. Management of this dog following treatment with Fab fragments was complicated by hypomagnesemia and loss of the positive inotropic effect of digoxin.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10613212/