Peer-reviewed veterinary case report
Treating dog nasal fungal infection with clotrimazole and rhinoscopy
By Vedrine, Bertrand & Fribourg-Blanc, Luc-André·Published in Journal of the American Animal Hospital Association·2018·From the Clinique Vé, France·View original on PubMed →
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Original publication title: Treatment of Sinonasal Aspergillosis by Debridement and Sinonasal Deposition Therapy with Clotrimazole Under Rhinoscopic Guidance.
- Species:
- dog
Plain-English summary
Ten dogs with sinonasal aspergillosis, a fungal infection affecting the nasal passages, underwent a procedure where their nasal cavities were cleaned of fungal plaques using a flexible endoscope. After the cleaning, a clotrimazole cream was applied directly to the affected areas without any oral medications. At follow-up visits, half of the dogs showed signs of being cured after the first check-up, while others improved over subsequent visits. However, two dogs experienced a return of the infection months later. Overall, this method of treatment appears effective and less invasive for managing sinonasal aspergillosis in dogs.
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Abstract
Rhinoscopy was performed on 10 dogs with sinonasal aspergillosis (SNA). Direct access to the sinus via the nasal ostium was possible with a flexible endoscope to allow sinuscopy. Debridement of fungal plaques in the frontal sinus and the nasal cavity was performed, and a sinus and nasal deposition therapy with clotrimazole (1%) cream was made under rhinoscopic guidance. No oral medication was administered following the procedure. A rhinoscopic follow-up was performed monthly until cure. Six of ten (60%) dogs presented fungal plaques in the nasal cavity and in the frontal sinus and 4/10 (40%) dogs presented fungal plaques only in the frontal sinus. Five of ten (50%) dogs were considered to be cured at the first follow-up rhinoscopy, 4/10 (40%) after the second follow-up, and 1/10 (10%) after the third. Two dogs had delayed recurrence of SNA rhinoscopically assessed 12 and 21 mo, respectively, after the last clotrimazole treatment. Endoscopic debridement of fungal plaques and clotrimazole (1%) cream deposition therapy seems to be a valuable minimally invasive technique for SNA treatment in dogs without the use of complementary oral medication. Delayed recurrence is a potential finding following treatment of SNA.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29372867/