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Peer-reviewed veterinary case report

Treatment and outcome of rectal plasmacytoma in dogs

By Jimeno Sandoval, Juan Carlos et al.·Published in Journal of the American Veterinary Medical Association·2025·1Anderson Moores Veterinary Specialists, United Kingdom·View original on PubMed

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Original publication title: Treatment, prognosis, and outcome of dogs treated for rectal plasmacytoma: a multicentric retrospective study.

Species:
dog

Plain-English summary

A group of 20 dogs with rectal plasmacytomas (a type of tumor) were treated either through surgery or with pain management. Most dogs underwent surgery, and while some experienced complications, the overall survival rates were promising, with 95% surviving for at least a year. However, about 31% of the surgically treated dogs had their tumors come back. Fortunately, none of the dogs progressed to a more serious condition called multiple myeloma. This suggests that while surgery can be effective, pet owners should be aware of the possibility of tumor recurrence.

People also search for: dog rectal tumor treatment · plasmacytoma in dogs · dog tumor recurrence · dog surgery complications · dog cancer survival rates

Abstract

OBJECTIVE: The aim of this study was to report the outcome and prognosis of canine patients treated medically or surgically for rectal plasmacytomas and to identify factors associated with recurrence, mortality, or progression to multiple myeloma. METHODS: The databases of 7 referral hospitals were reviewed. The Kaplan-Meier method and Cox proportional hazards analysis were used to determine the association of a range of variables with recurrence and progression-free interval for the surgically treated patients. RESULTS: 20 dogs were included. Nineteen cases were treated surgically, and 1 case was treated conservatively (analgesia and monitoring). Metastatic lesions were detected in 2 of 20 dogs (10%). Four of 19 dogs (21%) treated surgically developed postoperative complications, 1 major (1 of 19 [5.2%]) and 3 minor (3 of 19 [15.8%]). Tumor recurrence was identified in 6 of 19 dogs (31.5%). The 1-, 2-, and 3-year survival rates were 95%, 72%, and 66%, respectively. None of the variables tested were associated with occurrence of complications. Increased distance from the anus, incomplete surgical margins, and decreasing surgeon experience were associated with an increased risk of recurrence. No progression to multiple myeloma was seen in any of the cases. CONCLUSIONS: Surgical treatment of rectal plasmacytomas is associated with a low major complication rate and long survival. Metastasis and recurrence rates are significantly higher than previously reported. CLINICAL RELEVANCE: Conservative surgery leads to long-term survival, but recurrence is common. Future studies should focus on the benefits of adjuvant treatments.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39842084/