Peer-reviewed veterinary case report
Trilostane treatment for dogs with hyperadrenocorticism effects
By Ramsey, Ian K·Published in The Veterinary clinics of North America. Small animal practice·2010·Faculty of Veterinary Medicine, United Kingdom·View original on PubMed →
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Original publication title: Trilostane in dogs.
- Species:
- dog
Plain-English summary
Many dogs suffering from Cushing's disease (hyperadrenocorticism) are treated with a medication called trilostane, which helps lower cortisol levels in the body. Most dogs show improvement in their symptoms after starting this treatment, but it's important for pet owners to know that trilostane can have serious side effects, even though they are rare. Regular check-ups with the veterinarian are necessary to monitor the dog's health while on this medication. Overall, trilostane has been found to be effective for managing Cushing's disease in dogs.
People also search for: dog Cushing's disease treatment · trilostane side effects in dogs · how does trilostane work for dogs
Abstract
Over the last 10 years, trilostane, a competitive inhibitor of steroid synthesis, is being widely used for the treatment of canine hyperadrenocorticism. Trilostane causes a significant but reversible decrease in cortisol production and a concomitant improvement in clinical signs in most dogs with this common condition. Side effects, though infrequent, can be serious: dogs treated with this drug require regular monitoring. This review summarizes current knowledge of the use of this drug with particular emphasis on its efficacy, safety, adverse reactions, and effects on endocrine parameters. Brief mention is made of its other uses in dogs and other species.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20219488/