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Peer-reviewed veterinary case report

Cat with aggressive male behavior and adrenal enlargement

By Boag, A K et al.·Published in The Journal of small animal practice·2004·Department of Veterinary Clinical Sciences·View original on PubMed

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Original publication title: Trilostane treatment of bilateral adrenal enlargement and excessive sex steroid hormone production in a cat.

Species:
cat
Behaviour & energyCats

Plain-English summary

A 14-year-old neutered female cat was brought in for showing aggression and male-like behavior. Tests revealed that her adrenal glands were enlarged and she had high levels of hormones typically associated with male cats, but there were no signs of Cushing's disease. The veterinarian treated her with a medication called trilostane for six months, which helped improve her symptoms somewhat.

People also search for: cat aggression treatment · female cat hormone imbalance · trilostane for cats · cat adrenal gland enlargement symptoms

Abstract

A 14-year-old neutered female cat was presented for the investigation of aggression and male-type behaviour. Bilateral adrenal enlargement together with elevated plasma concentrations of oestradiol and testosterone were identified, with no evidence of hypercortisolaemia. These findings are similar to the syndrome of hyperadrenocorticism recognised most commonly in ferrets. The cat was treated for six months with the enzyme inhibitor drug, trilostane, and showed a moderate improvement in clinical signs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15163055/