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Peer-reviewed veterinary case report

Dog with jaw stiffness linked to hormone disorder and muscle issues

By Yokota, Shunya et al.·Published in The Journal of veterinary medical science·2023·Joint Graduate School of Veterinary Sciences, Japan·View original on PubMed

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Original publication title: Trismus due to myotonia associated with hyperadrenocorticism in a dog.

Species:
dog

Plain-English summary

A 13-year-old female Miniature Dachshund was brought in for a stiff gait and difficulty opening her mouth, known as trismus. She also had increased thirst and urination. Tests showed that her adrenal glands were enlarged, and she was diagnosed with hyperadrenocorticism (Cushing's disease). The vet treated her with a medication called trilostane, which helped her stiff gait somewhat, but her trismus did not improve over four months. More research is needed to understand how to better treat this condition in dogs.

People also search for: dog trismus treatment · Miniature Dachshund Cushing's disease symptoms · hyperadrenocorticism in dogs

Abstract

We present the report of trismus due to hyperadrenocorticism-associated myotonia diagnosed by electromyography in a dog. An intact female Miniature Dachshund, 13 years and 9 months old, presented with stiff gait and trismus as well as polyuria and polydipsia. Abdominal ultrasonography showed enlarged adrenal glands. An adrenocorticotropic hormone stimulation test revealed an exaggerated response. Based on these findings, this case was diagnosed with hyperadrenocorticism. Electromyography revealed myotonic discharge in the temporalis muscle and limbs. Therefore, trismus was considered to be caused by hyperadrenocorticism-associated myotonia, and the case was treated with oral trilostane (1.3 mg/kg, once daily). During the 4-month follow-up period, despite the partial improvement in stiff gait, trismus did not recover. Long-term data on more cases are warranted to assess the prognosis and clinical characteristics of trismus due to hyperadrenocorticism-associated myotonia.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37357395/