Peer-reviewed veterinary case report
Tuberculosis-like lesions arising from the use of Freund's complete adjuvant in an owl monkey (Aotus sp.).
- Journal:
- Journal of medical primatology
- Year:
- 2004
- Authors:
- Málaga, Carlos A et al.
- Affiliation:
- University of Puerto Rico
Abstract
An apparently normal, non-tuberculin-reacting, splenectomized owl monkey presented tuberculosis-like lesions of the lung at necropsy. Histological and bacteriological examination failed to demonstrate the presence of acid-fast organisms. Retrospective inquiry showed the animal had been inoculated using complete Freund's adjuvant during a malaria vaccine trial. Lesions observed were compatible with lipid embolism of the adjuvant in the lungs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15061724/