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Peer-reviewed veterinary case report

Turning back the clock on neurodegeneration.

Journal:
Cell
Year:
2007
Authors:
Mangan, Kile P & Levenson, Jonathan M
Affiliation:
Department of Physiology · United States

Abstract

Does neuronal loss associated with dementia necessarily impair the ability to learn new information and recall old memories? In a recent report in Nature, Fischer et al. (2007) show that the ability to learn and remember can be reestablished in a mouse model of dementia through either environmental enrichment or chronic treatment with an inhibitor of histone deacetylase.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17540162/