Peer-reviewed veterinary case report
Two juvenile dogs with skin disease causing hair loss and crusts
By Yoon, Ji-Seon et al.·Published in The Journal of veterinary medical science·2010·Tokyo University of Agriculture and Technology, Japan·View original on PubMed →
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Original publication title: Two dogs with juvenile-onset skin diseases with involvement of extremities.
- Species:
- dog
Plain-English summary
A 2-year-old mixed-breed dog and a 3-year-old Labrador were brought in for skin problems, including hair loss and crusty patches on their faces and legs. The first dog was diagnosed with a condition similar to junctional epidermolysis bullosa, which affects the skin's structure, while the second dog had a disease resembling dermatomyositis, which can affect the skin and muscles. Both conditions were identified through detailed skin tests. Treatment options may vary, so it's important to discuss specific care plans with your veterinarian.
People also search for: dog skin problems hair loss · juvenile skin disease in dogs · treatment for dog dermatomyositis
Abstract
Two dogs of juvenile-onset skin diseases with involvement of extremities were examined by histopathological, immunohistochemical and ultrastructural analyses. Clinically, both cases showed alopecia and crusts on the face and extremities. Case 1 showed histopathology of dermo-epidermal separation. Ultrastructural analysis revealed that the clefts were recognized between hemidesmosomes and lamina densa. In case 2, histopathology showed follicular atrophy, vacuolar degeneration at lower epidermis and masseter muscle degeneration, without remarkable ultrastructural abnormalities in basement membrane zone of the skin. Thus, the findings in case 1 were compatible to those in junctional epidermolysis bullosa, while those in case 2 were compatible to dermatomyositis-like disease. Combination of histopathological and ultrastructural analyses was useful to distinguish the diseases in two dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20622478/