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Peer-reviewed veterinary case report

Two models, one question: how does respiratory syncytial virus cause asthma?

Journal:
Trends in immunology
Year:
2026
Authors:
Hartert, Tina & Peebles, Ray Stokes
Affiliation:
Department of Medicine · United States

Abstract

De Leeuw et al. conducted human observational and murine studies to establish the combined role of parental aeroallergen sensitization and early-life respiratory syncytial virus infection in asthma development. The findings reveal synergistic effects driving immunological, pathological, and physiological changes resembling asthma, advancing the understanding of disease mechanisms and potential preventive targets.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41792009/